{"id":10336,"date":"2018-06-29T16:28:56","date_gmt":"2018-06-29T14:28:56","guid":{"rendered":"https:\/\/okomeds.com\/?p=10336\/"},"modified":"2020-08-31T20:15:58","modified_gmt":"2020-08-31T18:15:58","slug":"translational-medicine-and-medical-translation-for-cros","status":"publish","type":"post","link":"https:\/\/okomeds.com\/es\/translational-medicine-and-medical-translation-for-cros\/","title":{"rendered":"Translational medicine and Medical translation for CROs"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Translational medicine, or evidence-based research, is a bidirectional concept. It aims to improve human health by determining the relevance of <a href=\"https:\/\/okomeds.com\/new-discoveries-can-speed-clinical-translation\/\" target=\"_blank\" rel=\"noopener noreferrer\">novel discoveries <\/a>to disease, both coordinating knowledge and clinical practice and using direct human observation to characterize disease and generate new hypotheses. Medical translation is essential in any event, as it plays a key role in clinical evidence-based research.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Introduced in the 1990s the term was not spread until the early 2000s. Nevertheless, since the beginning, this practice has enhanced interdisciplinary collaborations, the use of advanced technologies, and therapeutics, applying what has been revealed in preclinical evidence-based research safely to clinics. Anyway, international clinical tests in traslational medicine need to conform to the Declaration of Helsinki (World Medical Association), and therefore, the test language must be understood by both doctors and patients.<\/span><\/p>\n<p>&nbsp;<\/p>\n\r\n        <a href=\"https:\/\/twitter.com\/intent\/tweet?text=New types of CROs are arising, affecting medical science from concept to market&url=&via=okomeds\" class=\"retweet-okodia\" >New types of CROs are arising, affecting medical science from concept to market <div class=\"retwitear-ok\" style=\"text-align: right;   font-size: 10px; padding-right: 43px;\">Tweet!<\/div><\/a>\r\n        <script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0];if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=\"\/\/platform.twitter.com\/widgets.js\";fjs.parentNode.insertBefore(js,fjs);}}(document,\"script\",\"twitter-wjs\");<\/script>\n<p>&nbsp;<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Alternar tabla de contenidos\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/okomeds.com\/es\/translational-medicine-and-medical-translation-for-cros\/#CROs_and_Medical_Translators_pivotal_roles_in_the_chain_from_discovery_to_market\" >CROs and Medical Translators pivotal roles in the chain from discovery to market<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/okomeds.com\/es\/translational-medicine-and-medical-translation-for-cros\/#The_fusion_between_biologics_and_devices_and_other_market_changes_Medical_Translation_is_still_basic\" >The fusion between biologics and devices, and other market changes. Medical Translation is still basic<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"CROs_and_Medical_Translators_pivotal_roles_in_the_chain_from_discovery_to_market\"><\/span><b>CROs and Medical Translators pivotal roles in the chain from discovery to market<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">CROs have emerged as functional aspects specialists. They continuously diversify following expanding market demands and new types of CROs are arising, affecting medical science from concept to market. This evolution encourages expansion and multi-site clinical trials, which usually require multiple languages documents.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">From utility companies for Sponsors, <a href=\"https:\/\/okomeds.com\/clinical-research-translation-news-april-cro-special\/\" target=\"_blank\" rel=\"noopener noreferrer\">CROs<\/a> can nowadays suit sophisticated demands of medical, pharmaceutical and device industries, such as tissue engineering repairs, biocompatibility of implants, or pharmacodynamics. There is, however, a well-known division among CROs: Preclinical CROs which deal, among others, with matters related to drug screening, device manufacturing, toxicology or compound synthesis. And Clinical CROs that mainly deal with regulatory requirements and the human aspect of the trials.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this sense, CROs require reliable results that add value to the product development process. Every project must be carefully documented and efficiently managed. And, on top of that, Sponsors must receive on-time translations. CROs are essential to dissemination of scientific evidence-based research and to promote the development of society and traslational medicine. That dissemination implies, different localizations and different languages, that must be mastered to facilitate the results of any study, as communication is an essential part of them.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">New CROs functions include assisting disease diagnosis, introducing <a href=\"https:\/\/okomeds.com\/personalized-lifestyle-medicine-translation\/\" target=\"_blank\" rel=\"noopener noreferrer\">personalized care<\/a> or visualizing disease progression, being essential to deliver translational medicine, as the number of new drugs or medical devices under development continues to grow. Medical <a href=\"https:\/\/okomeds.com\/translation-cro\/\" target=\"_blank\" rel=\"noopener noreferrer\">translation for CROs<\/a>, on the other hand, must be built on the understanding that <\/span><span style=\"font-weight: 400;\">what is needed is reliable results that add value to the product development process.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-10339 size-full\" src=\"https:\/\/okomeds.com\/wp-content\/uploads\/2018\/06\/T-J-1.2.png\" alt=\"Translational medicine and Medical translation for CROs 2\" width=\"1024\" height=\"512\" srcset=\"https:\/\/okomeds.com\/wp-content\/uploads\/2018\/06\/T-J-1.2.png 1024w, https:\/\/okomeds.com\/wp-content\/uploads\/2018\/06\/T-J-1.2-300x150.png 300w, https:\/\/okomeds.com\/wp-content\/uploads\/2018\/06\/T-J-1.2-768x384.png 768w, https:\/\/okomeds.com\/wp-content\/uploads\/2018\/06\/T-J-1.2-1000x500.png 1000w, https:\/\/okomeds.com\/wp-content\/uploads\/2018\/06\/T-J-1.2-700x350.png 700w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"The_fusion_between_biologics_and_devices_and_other_market_changes_Medical_Translation_is_still_basic\"><\/span><b>The fusion between biologics and devices, and other market changes. Medical Translation is still basic<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Evolution has, in the first place, reduced delineation between biologics and devices. Therefore, demands for clinical practices, regulatory reviews or health care operations have also evolved, although regulatory requirements for clinical trial remain, despite translational medicine, or evidence-based research. This explains why quality control procedures that ensure complete translation process by medical and linguist experts is mandatory.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pharmaceutical companies are interested in integrated services from a single CRO. However, bearing in mind that this request has the same pitfalls of the old system, a successful alternative, that joins the specialization of CROs and the one-window shop to facilitate achieving goals on-time, is Expertise-Based Integrated Service (EBIS) concept which is compatible with translational medicine, or evidence-based research focus.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although the pharmaceutical industries initially hold intellectual properties, joint ventures and mergers and acquisitions have blurred the initial structure between companies and brands, aiming to convince regulatory bodies and even corporate partners. Nowadays, CROs can also hold IP.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The often needed back translation, cognitive debriefing or harmonization of the patient responses, still persists too in translational medicine. No wonder, as data must be accurate and consistent in all the languages that are needed for the trials. Without it, data analysis cannot be correctly performed, which implies that faulty or inaccurate translations can render trials inadequate. Can you imagine the drug company loses?<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Translational medicine, or evidence-based research, is a bidirectional concept. It aims to improve human health by determining the relevance of novel discoveries to disease, both coordinating knowledge and clinical practice and using direct human observation to characterize disease and generate new hypotheses. Medical translation is&#8230;<\/p>\n","protected":false},"author":1,"featured_media":10338,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5,280],"tags":[224,257,192,331,268,190,191,329,59,328,322,327,332,326,325,111,324,277,323,330,205,321],"class_list":["post-10336","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-research","category-translation-for-cros","tag-clinical-research","tag-clinical-trial-protocol","tag-clinical-trials","tag-compound-synthesis","tag-contract-research-organization","tag-cro","tag-cros","tag-device-manufacturing","tag-doctor","tag-drug-screening","tag-evidence-based-research","tag-expertise-based-integrated-service","tag-human-aspect-of-the-trials","tag-linguist-experts","tag-medical-experts","tag-patient","tag-quality-control-procedures","tag-regulatory-requirements","tag-sponsor","tag-toxicology","tag-translation-for-cros","tag-translational-medicine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Translational medicine and Medical translation for CROs - Okomeds<\/title>\n<meta name=\"description\" content=\"Translational medicine, or evidence-based research, aims to improve human health by determining the relevance of novel discoveries to disease, both coordinating knowledge and clinical practice and using direct human observation. 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